Top drugs for the PTCB exam

Medications are 35% of the PTCE, and outline item 1.1 is generic names, brand names and classifications - start with these commonly prescribed drugs and the suffix patterns.

Updated 2026-09-23 · 3 sources · By the HealthCert Prep team

Educational exam prep, not medical advice. This page teaches what certification exams test. Follow your facility’s policies, your supervising clinician and the manufacturer’s instructions in practice. If you are a patient with a health question, talk to your clinician or see MedlinePlus.

Commonly prescribed drugs

Our curated study list, not an official "top 200." Rankings by US prescription volume are published by ClinCalc DrugStats; labeling facts per FDA/DailyMed.
GenericBrandClassMain use
atorvastatinLipitorHMG-CoA reductase inhibitor (statin)High cholesterol
levothyroxineSynthroidThyroid hormoneHypothyroidism
lisinoprilZestril, PrinivilACE inhibitorHypertension, heart failure
metforminGlucophageBiguanideType 2 diabetes
amlodipineNorvascCalcium channel blockerHypertension, angina
metoprololLopressor, Toprol XLBeta blockerHypertension, angina, heart failure
omeprazolePrilosecProton pump inhibitorGERD, ulcers
losartanCozaarAngiotensin II receptor blockerHypertension
albuterolProAir, VentolinShort-acting beta-2 agonistAsthma, COPD (rescue)
gabapentinNeurontinAnticonvulsantSeizures, nerve pain
hydrochlorothiazideMicrozideThiazide diureticHypertension, edema
sertralineZoloftSSRIDepression, anxiety
montelukastSingulairLeukotriene receptor antagonistAsthma, allergies
escitalopramLexaproSSRIDepression, anxiety
rosuvastatinCrestorStatinHigh cholesterol
bupropionWellbutrinAminoketone antidepressantDepression, smoking cessation
furosemideLasixLoop diureticEdema, heart failure
pantoprazoleProtonixProton pump inhibitorGERD
trazodoneDesyrelAntidepressant (SARI)Depression
tamsulosinFlomaxAlpha-1 blockerEnlarged prostate (BPH)
fluoxetineProzacSSRIDepression, OCD
carvedilolCoregBeta blocker (alpha/beta)Heart failure, hypertension
duloxetineCymbaltaSNRIDepression, nerve pain
meloxicamMobicNSAIDArthritis
clopidogrelPlavixAntiplatelet (P2Y12 inhibitor)Prevent clots after MI/stroke
prednisoneDeltasone (brand discontinued)CorticosteroidInflammation
insulin glargineLantusLong-acting insulinDiabetes
tramadolUltramOpioid analgesic (C-IV)Pain
apixabanEliquisFactor Xa inhibitorPrevent clots, AFib stroke prevention
warfarinJantovenVitamin K antagonistPrevent clots
glipizideGlucotrolSulfonylureaType 2 diabetes
spironolactoneAldactonePotassium-sparing diureticHeart failure, edema
allopurinolZyloprimXanthine oxidase inhibitorGout
amoxicillinAmoxilPenicillin antibioticBacterial infections
azithromycinZithromaxMacrolide antibioticBacterial infections
alprazolamXanaxBenzodiazepine (C-IV)Anxiety, panic disorder
zolpidemAmbienSedative-hypnotic (C-IV)Insomnia
hydrocodone/acetaminophenNorcoOpioid combination (C-II)Pain
amphetamine/dextroamphetamineAdderallCNS stimulant (C-II)ADHD
empagliflozinJardianceSGLT2 inhibitorType 2 diabetes, heart failure
semaglutideOzempicGLP-1 receptor agonistType 2 diabetes

Suffixes that reveal the class

SuffixClassExample
-prilACE inhibitorlisinopril
-sartanARBlosartan
-olol / -ilolBeta blockermetoprolol, carvedilol
-dipineCalcium channel blockeramlodipine
-statinStatinatorvastatin
-prazoleProton pump inhibitoromeprazole
-tidineH2 blockerfamotidine
-gliflozinSGLT2 inhibitorempagliflozin
-glutideGLP-1 agonistsemaglutide
-gliptinDPP-4 inhibitorsitagliptin
-azepam / -azolamBenzodiazepinelorazepam, alprazolam
-cillinPenicillinamoxicillin
-floxacinFluoroquinoloneciprofloxacin
-cyclineTetracyclinedoxycycline
-xabanFactor Xa inhibitorapixaban

How it is tested

Expect brand-to-generic matching, class identification, indications, common side effects and storage. Controlled-substance schedules for drugs like alprazolam (C-IV) and hydrocodone combinations (C-II) cross over into pharmacy law.

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Frequently asked questions

Do I need to memorize the top 200 drugs for the PTCB?

The outline tests generic/brand names, classes and indications broadly; the most-prescribed 100-200 drugs are the practical study set.

What is the brand name of atorvastatin?

Lipitor.

What class is lisinopril?

An ACE inhibitor - the -pril suffix gives it away.

Sources

  1. PTCB - PTCE Content Outline effective January 6, 2026 (accessed 2026-09-23)
  2. NLM DailyMed - FDA drug labeling (accessed 2026-09-23)
  3. ClinCalc DrugStats - Top 300 drugs by US prescriptions (accessed 2026-09-23)